Children Can Achieve Clinical Remission Of Peanut Allergy With Oral Immunotherapy
Oral immunotherapy with or without probiotic adjuvants conferred sustained unresponsiveness to peanut among allergic children, according to a randomized phase 2b study published in The Lancet Child & Adolescent Health. Although the probiotic adjuvant did not improve remission rates, it may improve the safety and tolerability of OIT, research found.
It is the first randomized controlled study of peanut oral immunotherapy to show high rates of sustained responsiveness in school-aged children and the first to show that a peanut allergy treatment can provide substantial improvement in quality of life compared to current standard of care of peanut avoidance, author Mimi L.K. Tang,MBBS, PhD, FRACP, FRCPA, FAAAAI, CEO of Prota Therapeutics and professor at Murdoch Childrens Research Institute in Melbourne, Australia, said in a press release.
The studys rollout
The 4-year study involved children aged 1 to 10 years with confirmed peanut allergies, with 79 participants assigned a probiotic and PRT120 peanut oral immunotherapy , 83 participants assigned a placebo probiotic and peanut OIT, and 39 participants assigned placebo probiotic and placebo peanut OIT at three hospitals in Australia. On day 1, participants received 2 x 1010 colony-forming units of Lactobacillus rhamnosus ATCC 53103 probiotic or placebo before receiving increasing doses of peanut protein or placebo every 20 minutes until they reached a dose of 12 mg, with a cumulative total of 24 mg.
The studys results
Food Diversity In The First Year Of Life Leads To Fewer Allergies In The Second Year
Infants who ate a more diverse diet during their first year had lower risk for allergic diseases during their second year, according to a study published in Pediatric Allergy and Immunology.
Chunrong Zhong, PhD, of Tongji Medical College at Huazhong University of Science and Technology in Wuhan, China, and colleagues surveyed 2,251 women who gave birth to singleton live infants at 1, 3, 6, 12 and 24 months after birth.
Pediatric Allergy and Immunology.
The women were asked about breastfeeding, use of formula, complementary foods introduced and history of food allergies among their infants. The researchers then assessed food diversity by the number of food groups introduced to each infant. For the 6-month interview, the researchers categorized complementary foods into cereal, vegetable, fruit, meat, fish and egg groups. They found that 44% of the infants had been introduced to three to six of these groups. Cereals represented the most introduced food group, followed by fruits, egg yolk and vegetables.
In models adjusted for food allergy history of infants and other potential confounders, the researchers found significant inverse dose-response relationships with food diversity by 12 months of age and later allergic diseases , especially when those diseases involved the respiratory tract . Infants only exposed to one to five food groups by 12 months of age also had an increased odds of food allergy during 1 to 2 years of age .
Posted on March 07, 2022 |Permalink
Keeping Allergies And Asthma Under Control In The New Year
From the ACAAI:
New Years resolutions can feel overwhelming, and guilt-inducing if you cant keep them. This year, why not assign yourself a few tasks to keep your allergy and asthma symptoms under control in 2022, while making sure you dont get COVID-19?
The best way to tackle health challenges is in small bits, and that goes for allergy and asthma control, says allergist Mark Corbett, MD, president of the American College of Allergy, Asthma and Immunology . The last few years have been hard on everyone, but you still want to figure out ways to improve your health routine. Making small, manageable adjustments is a great start to getting on a healthier path and seeing improvements in controlling allergy and asthma flares.
Following are five New Years resolutions from ACAAI those who suffer from allergies or asthma may want to consider.
For more information about treatment of allergies and asthma, and to locate an allergist in your area, visit AllergyAndAsthmaRelief.org.
To read more, click here
Posted on December 19, 2021 |Permalink
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Children Who React To First Covid Vaccine Dose Can Safely Receive Second Dose
Children with immediate allergic reactions to their first dose of the Pfizer-BioNTech COVID-19 vaccine safely received the second dose, according to a study published in The Journal of Allergy and Clinical Immunology: In Practice. Children with a history of allergy to polyethylene glycol or polysorbate also safely received the second dose, Joel P. Brooks, DO, MPH, staff allergist and immunologist at Childrens National Hospital in Washington, D.C., and colleagues wrote in the study
We began this study as we were receiving several referrals at Childrens National Hospital from the community regarding patients who had reactions to their first dose of their Pfizer-BioNTech COVID-19 vaccine, Brooks told Healio. We sought to help these families protect themselves during the COVID-19 pandemic by completing their vaccination cycle.
When the COVID-19 vaccines first became available, the CDC recommended that patients who experienced reactions to a first dose abstain from receiving a second. Studies later reported that adults with these histories who received a second dose did so safely. However, the researchers indicated that there have been no similar studies among children, with limited guidance for evaluating and proceeding with the second dose for children who reacted to the first dose.
Safe second shots
Talking with patients, parents
Posted on August 14, 2022 |Permalink
First Treatment Approved For Eosinophilic Esophagitis
Dupilumab became the first drug approved to treat eosinophilic esophagitis in adults and pediatric patients ages 12 and older weighing at least 40 kg , the FDA announced. Eosinophilic esophagitis is a chronic, progressive disease in which the esophagus becomes inflamed due to a buildup of eosinophils, creating difficulty swallowing and eating. Dupilumab is a monoclonal antibody that acts to inhibit part of the inflammatory pathway, blocking interleukin-4 and -13 receptors. “As researchers and clinicians have gained knowledge about eosinophilic esophagitis in recent years, more cases of the disorder have been recognized and diagnosed in the U.S.,” Jessica Lee, MD, director of the division of gastroenterology in the FDA’s Center for Drug Evaluation and Research, said in a statement. “Today’s approval will fulfill an important unmet need for the increasing number of patients with eosinophilic esophagitis,” she added.
The most common side effects associated with dupilumab include injection site reactions, upper respiratory tract infections, joint pain, and herpes viral infections, the FDA said. The drug is contraindicated for patients with known hypersensitivity to dupilumab or any of its inactive ingredients. Dupilumab carries warnings and precautions about the potential development of allergic reactions, conjunctivitis, keratitis, or joint pain use in patients with certain parasitic infections and use in conjunction with live vaccinations, the agency added.
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Ridgefield Ct Asthma Allergy & Immunology Specialists
The allergists in our Ridgefield office specialize in the evaluation, diagnosis and treatment of both pediatric and adult asthma, food allergies, seasonal and environmental allergies, drug and medication allergies, as well as venom, bee, skin, nasal and eye allergies. Our allergy specialists are to support you from your first to your last appointment.
Our Monroe Office Has Moved To Trumbull
Allergy & Asthma Care of Fairfield County is excited to announce that our Monroe office has moved to a beautiful new location 1.5 miles down Route 111 at 35 Corporate Drive, Trumbull, CT. Our Trumbull office hours will be the same as our previous Monroe office hours.
Our Fairfield office has not moved, and remains at 55 Walls Drive, Suite 405, Fairfield, CT.
Posted on August 11, 2021 |Permalink
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We’ve Moved Our Fairfield Office
Allergy & Asthma Care of Fairfield is excited to announce that our Fairfield office has moved to a bigger, better space in the same building, 55 Walls Drive, Suite 105, on the first floor of the building. We have more rooms for patients so we can continue to offer all of the excellent care you’ve come to expect, plus continue to expand our oral immunotherapy / desensitization to foods program that applies the latest advances in food allergy management. We continue to remain at the forefront of allergy treatment, and are excited to be able to expand this life-changing program for our food allergy patients. We look forward to welcoming you to our brand new space. Please excuse some of the missing furniture and ongoing millwork, as supply chain issues have led to some delays in updating our office chairs, cabinetry, etc.
Posted on July 10, 2022 |Permalink
Chemicals Found In Household Products May Increase Risk Of Asthma In Adults
Commonly-used household products should carry a warning that they increase the risk of asthma, according to a new evidence review. New research conducted by Smartline, a research project funded by the European Regional Development Fund, finds evidence that a group of chemicals found in a wide range of products in peoples homes increases the risk of asthma. Authors conclude that labelling should reflect this risk and warn people to ventilate their homes while using them. The research reviewed 12 studies into Volatile Organic Compounds , which are emitted as gases from certain solids or liquids. VOCs are emitted by a wide array of products, including some that are widely used as ingredients in household products. Paints, varnishes and wax, many cleaning, disinfecting, cosmetic, degreasing and hobby products may all contain ingredients that emit VOCs. Concentrations of many VOCs are consistently up to ten times higher indoors than outdoors.
One highly regarded study found a 15 per cent increased risk of asthma with exposure to Limonene, a naturally occurring aliphatic compound found in products like shampoos, detergents and air fresheners. Wood and kitchen paint also seem to increase symptoms.
Posted on July 23, 2021 |Permalink
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Combination Nasal Medication Treatment Improves Nasal Allergy Symptoms Better Than One Alone
Intranasal corticosteroid and intranasal antihistamine therapies did a better job of alleviating nasal and ocular symptoms in allergic rhinitis than intranasal corticosteroid therapy alone, according to a review. Examples of these medications include fluticasone or mometasone nasal sprays plus azelastine or olopatadine nasal sprays
The combination also more significantly improved quality of life, Minji Kim, MD, PhD, of the department of pediatrics at Chungnam National University Sejong Hospital, Sejong, Korea, and colleagues wrote in the review, which was published in Allergy. The review assessed 13 randomized controlled trials, with 10 evaluating differences in symptom scores and 12 describing adverse events. The combination of intranasal corticosteroid and intranasal antihistamine therapies produced a more significant reduction in mean morning and evening 12-hour reflective total nasal symptom scores than INCS monotherapy .
The combination also produced a more significant reduction in total ocular symptom scores than INCS monotherapy . However, it did not lead to a more significant reduction in total symptom score .Further, total mean Rhinoconjunctivitis Quality of Life Questionnaire scores significantly improved with the combined therapy . However, the combination treatment did not exceed the thresholds of minimally clinically important differences of 0.28 for TNSS or 0.5 for RQLQ.
Posted on August 14, 2022 |Permalink
Severe Asthma Exacerbations Associated With Short Acting Beta Agonist Use
Increasing exposure to short-acting beta 2 agonist rescue or reliever medication appeared associated with greater risk for severe asthma exacerbations regardless of inhaled corticosteroid use, according to study results. Published in The Journal of Allergy and Clinical Immunology: In Practice, the study results suggest that rescue/reliever management using short-acting beta 2 agonist monotherapy should be avoided, according to the researchers.
Jennifer K. Quint, MD, PhD, FRCP, professor of respiratory epidemiology at Imperial College London National Heart and Lung Institute, and colleagues examined data from 1,033,564 patients in the SABa use IN Asthma series of observational studies including 10 North American and European datasets. Patients were aged 12 years and older with asthma and had been prescribed or possessed at least one SABA canister per year. Mean ages ranged across the datasets from 23.2 years to 72.2 years , and most patients were women .
The exception was the dataset based on Medicare findings, in which patients who were prescribed or who possessed one or two canisters per year saw higher incidence of severe exacerbations than patients with three or more canisters per year . Patients who had GINA scores of three to five and three or more prescriptions or possessions of SABA canisters per year experienced more severe exacerbations than patients with fewer canisters per year across all countries and datasets.
Posted on April 17, 2022 |Permalink
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About Allergy And Asthma Consultants Of Fairfield County Llc
Allergy And Asthma Consultants Of Fairfield County, LLC is an allergist & immunologist practice located inFairfield, CT.
The doctors and healthcare providers related to Allergy And Asthma Consultants Of Fairfield County, LLC include:
- Aimee S. Altschul-Latzman, MDis an allergist & immunologistwho practicesallergy & immunology and other service specialty.
- Brittany Craiglow, MDis a dermatologistwho practicesdermatology and pediatric dermatology.
Allergy And Asthma Consultants Of Fairfield County, LLC has been registered with the National Provider Identifier databasesince January 18, 2013and its NPI number is1992043483.
Book an Appointment
To schedule an appointment, please call 955-1461.
Goats Milk Skin Product Usage May Lead To Severe Goats Milk Allergy
A small cohort of patients who used goats milk-containing treatments for inflammatory skin conditions subsequently developed severe goats milk allergy, according to a research letter published in Clinical & Experimental Allergy. This case series adds to the research suggesting that application of food-based skin care products to inflamed skin can lead to the development of new food allergies, according to Joseph Francis De Luca, a PhD candidate in the department of medicine at University of Melbourne in Australia, and colleagues.
Researchers noted growing numbers of patients using topical goats milk products to manage inflammatory dermatopathies and then developing systemic reactions to goats milk or cheese ingestion. Theorizing that this sensitization began due to the topical exposure to goat products, the researchers conducted a retrospective audit of all specific IgE results for goats and/or sheeps milk tallied by the Royal Melbourne Hospital pathology department between 2016 and 2019. They identified seven patients who experienced symptoms consistent with IgE-mediated reactions to ingested goats or sheeps milk or cheese products had used topical goats milk products to manage inflammatory conditions before their allergy emerged. Six of these patients had atopic dermatitis, and five had allergic rhinitis.
Posted on April 11, 2022 |Permalink
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Connecticut Asthma And Allergy Center
Please read the following in advance of your appointment.
CAAC COVID-19 Office Regulations
CAAC is dedicated to keeping our patients and staff protected from exposure to COVID-19.
- We require ALL patients over 2 years of age to wear well-fitting cloth or surgical mask when they come in. If you or your child are unable to wear a well-fitted cloth or surgical mask, please notify our scheduling team upon booking your appointment as we may need to make special accommodations for you.
- For Allergy Shot visits: We are asking ALL patients to not bring additional family members to appointments. Minors should be accompanied by only one adult. Siblings and other family members will not be permitted into the office unless they are also scheduled to be seen.
- For Office Visits: Patients aged 0-4 years old – Both parents can attend the office visit. Both Parents need to be symptom free and wear a well fitting mask. Patients aged 5-18 – Only 1 parent should be in attendance in the office, if both parents would like to attend we can set up a Zoom call for you to join. Patients 18-22 – 1 Parent can attend the visit. We are still asking that siblings without office visits and addition family members not attend the appointment.
- Patients with office visit appointments in all offices will be checked in by phone and wait in their car for an exam room to open.
Nearly 30% Of Peanut Allergies And 90% Of Egg Allergies Resolve By Age 6
About three out of 10 peanut allergies and nine of 10 egg allergies resolved by age 6 years, although infants with early-onset severe eczema or multiple allergies were less likely to outgrow them, according to a longitudinal study.
These findings may inform the use of disease-modifying treatments such as oral immunotherapy or proactive treatment of eczema in early life, the researchers wrote in the study, which was published in The Journal of Allergy and Clinical Immunology.
J Allergy Clin Immunol
Prioritizing research of these and future interventions for infants less likely to naturally outgrow their allergy would yield the most benefit for health care resources and research funding, Rachel L. Peters, PhD, associate professor, epidemiologist and team lead within the population allergy research group at Murdoch Childrens Research Institute, Royal Childrens Hospital, in Parkville, Victoria, Australia, said in a press release.
Among the 471 children with raw egg allergy at age 1 year, allergies resolved in 89% of those with definite allergy by age 6 years. Additionally, compared with children whose egg allergy had resolved, persistent egg allergy was more likely among children with an SPT result of 4 mm or larger , peanut or sesame food sensitizations , early-onset severe eczema and baked egg allergy when aged 1 year.
Posted on May 26, 2022 |Permalink
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New Biologic Tezepelumab Shows Efficacy In Severe Asthma During All Seasons
Dr. Kenneth Backman of Allergy & Asthma Care comments: “Tezepelumab offers another option for severe asthma, and is the first biologic for asthma that has no limitations in prescribing regarding allergic antibody levels or allergy white blood cell levels Tezepelumab offers a wide range of asthma patients a treatment that can reduce the need for corticosteroid medications.”
Posted on February 08, 2022 |Permalink
Posted on January 22, 2022 |Permalink
Allergy And Asthma Care Of Fairfield County Llc
Detailed information about Allergy And Asthma Care Of Fairfield County LLC in Fairfield Connecticut.
Allergy And Asthma Care Of Fairfield County LLC is a Medical Group that has only one practice medical office located in Fairfield CT. There are 3 health care providers, specializing in Allergy/Immunology, Internal Medicine, Nurse Practitioner, being reported as members of the medical group. Medical taxonomies which are covered by Allergy And Asthma Care Of Fairfield County LLC include Family, Allergy & Immunology, Internal Medicine.
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