The Impact Of Asthma On Daily Life
Asthma is often under-diagnosed and under-treated, particularly in low- and middle-income countries.
People with under-treated asthma can suffer sleep disturbance, tiredness during the day, and poor concentration. Asthma sufferers and their families may miss school and work, with financial impact on the family and wider community. If symptoms are severe, people with asthma may need to receive emergency health care and they may be admitted to hospital for treatment and monitoring. In the most severe cases, asthma can lead to death.
Identify Your Triggers To Skip Them
There are a lot of things that might trigger asthma symptoms and they vary from person to person. If you know your asthma triggers like allergens and irritants that worsen your asthma by irritating your airways, you can easily skip them. Knowing your asthma trigger is the best practice for controlling your asthma.
Whats Different About Severe Asthma
But someone with severe asthma struggles to manage their symptoms even with high doses of medicines.
And sometimes it can take a while to find a combination of medicines and doses that works best for you.
Even if your asthma is difficult to control, its not the same as severe asthma. If you have difficult to control asthma you should be able to get on top of your symptoms with support from your GP or asthma nurse, with an action plan, regular reviews and a good routine of taking your asthma medicines.
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Diagnosing Asthma In Children Younger Than 6
It can be hard to tell whether a child under age 6 has asthma or another respiratory condition, because young children often cannot perform a pulmonary function test such as spirometry. After checking a childs history and symptoms, the doctor may try asthma medicines for a few months to see how well a child responds. About 40% of children who wheeze when they get colds or respiratory infections are eventually diagnosed with asthma.
Whats The Outlook For People With Asthma
Most people with asthma are able to manage symptoms and maintain a good quality of life.
An acute exacerbation of asthma can be a life-threatening event. However, you should be able to resume your normal activities once its under control. Of course, youll want to avoid known triggers and follow your doctors advice for management of your asthma.
If you have asthma, you should have an action plan in place. Work with your doctor to come up with a plan so youll know what to do when symptoms flare up.
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Maintain Your Fitness Through Exercising
If you want to maintain a normal and healthy life then there is no alternative to exercise. But when you have an asthma problem you should do your exercise carefully as sometime it could trigger your asthma problem as well. So its better to make your exercise plan by consulting your doctor or health care provider.
With the right exercise you can improve your breathing muscles, promote your immune system, and maintain a healthy lifestyle. Along with your physical activity you can use this Handheld Breath Training Device for an effective breathing exercise to improve your lung capacity.
For your safety precaution before doing any exercise, you need to make sure that your asthma is under control. Otherwise it may worsen your asthma symptoms.
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What Types Of Asthma Are There
Healthcare providers identify asthma as intermittent or persistent . Persistent asthma can be mild, moderate or severe. Healthcare providers base asthma severity on how often you have attacks. They also consider how well you can do things during an attack.
Asthma can be:
- Allergic: Some peoples allergies can cause an asthma attack. Molds, pollens and other allergens can cause an attack.
- Non-allergic: Outside factors can cause asthma to flare up. Exercise, stress, illness and weather may cause a flare.
Who Can Get Asthma
Anyone can develop asthma at any age. People with allergies or people exposed to tobacco smoke and secondhand smoke are more likely to develop asthma.
Statistics show women tend to have asthma more than men, and asthma affects Black Americans more frequently than other races.
When a child develops asthma, healthcare providers call it childhood asthma. If it develops later in life, its adult-onset asthma.
Children do not outgrow asthma. They may have fewer symptoms as they get older, but they could still have an asthma attack. Your childs healthcare provider can help you understand the risks.
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Changes Of Vegf In Sera And Induced Sputa During Long Term Follow
shows the changes of VEGF level of group I subjects in induced sputum during 2 yr follow-up period. Sputum VEGF level showed variable changes at 1-yr, which decreased significantly at 2-yr after the diagnosis . shows changes of serum VEGF levels during 4 yr follow-up period. Serum VEGF level showed variable changes at 2-yr after the diagnosis , which decreased significantly at 4-yr . There were no significant correlations between VEGF levels in both sputum and sera with clinical parameters including FEV1 values and airway hyperresponsiveness to methacholine . Also no significant correlation was found between VEGF level and neutrophil and eosinophil count in the sputum .
Role Of Immune System In Asthma
The development of asthma in response to environment and allergies are closely linked to Th1-type, Th2-type, and IgE immune responses. Th1-type immune responses are linked to fighting infection while Th2-type responses are linked to allergies. In asthma Th2-type responses are more active leading to allergies and asthma. IgE responses are linked to allergies. IgE known as immunoglobulin E will bind to the allergen and then to a mast cell, which causes the release of histamine. Histamine causes inflammation and excess mucous production.
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Whats An Asthma Attack
When you breathe normally, muscles around your airways are relaxed, letting air move easily. During an asthma attack, three things can happen:
- Bronchospasm: The muscles around the airways constrict . When they tighten, it makes the airways narrow. Air cannot flow freely through constricted airways.
- Inflammation: The airway linings become swollen. Swollen airways dont let as much air in or out of the lungs.
- Mucus production: During the attack, your body creates more mucus. This thick mucus clogs airways.
How Long Asthma Lasts For
Asthma is a long-term condition for many people, particularly if it first develops when you’re an adult.
In children, it sometimes goes away or improves during the teenage years, but can come back later in life.
The symptoms can usually be controlled with treatment. Most people will have normal, active lives, although some people with more severe asthma may have ongoing problems.
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Strategies For Addressing Asthma In Schools
CDCs Strategies for Addressing Asthma in Schools guide provides a compilation of information and resources for implementing asthma programs in schools. Although it was designed for staff in state health departments, school systems with an interest in asthma friendly schools have found it to be useful.
Chronic Allergen Challenge Models
In order to address some of the issues associated with acute challenge models, several research groups have investigated chronic allergen exposure in mice. The key aims were to reproduce more of the features of clinical asthma, such as airway remodelling and persistent AHR, and to enable novel therapies to be evaluated in a therapeutic setting rather than a prophylactic setting, i.e. evaluating the effect of a novel drug in an established pulmonary inflammation setting. A number of different chronic challenge models have been developed by increasing the number of allergen challenges, some examples are shown in . Kumar et al. and Lloyd have discussed some of these models in recent review articles .
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What Are The Symptoms Of Asthma
Common symptoms of asthma are listed below. However, each individual may experience symptoms differently.
In some cases, the only symptom is a chronic cough, especially at night, or tightness, noisy breathing, or wheezing. Some people think they have recurrent bronchitis, since respiratory infections usually settle in the chest in a person predisposed to asthma.
Asthma may resemble other respiratory problems, such as emphysema, bronchitis, and lower respiratory infections. Many people with asthma do not know they have it. Consult your doctor for a diagnosis.
Latest Treatments For Severe Asthma
In recent years a new type of treatment has been developed using monoclonal antibodies, known as mAbs or biologics therapies.
These treatments can dramatically improve the lives of people with certain types of severe asthma and can cut down the dose of steroids they are taking and lead to a better quality of life.
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How Is Asthma Prevented And Treated
There is no cure for asthma. Control symptoms by taking asthma medicines and avoiding your triggers. With proper treatment and an asthma management plan, you can reduce your symptoms and enjoy a better quality of life.
Talk to your health care provider about your asthma symptoms and be sure to discuss any changes in your asthma management or status.
Will My Wheezing Or Coughing Be Worse
Not necessarily. You might be surprised to learn that you may not have more of these than usual during a severe asthma attack. So donât judge how bad your asthma attack is based on how much you wheeze or cough.
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Where Definitions Fall Short
As tidy as the definitions may seemsix months or more for chronic versus less than six months for acutethese timeframes in no way suggest what you may be faced with if diagnosed with an acute or chronic illness.
In the end, labeling an illness as acute or chronic cannot describe the nature of a disease, nor predict outcomes.
This non-specificity of definitions not only affects doctors and patients but also researchers who look for concise ways to evaluate the course of a disease. Thresholds are frequently changed from six months to three months or extended to a year or more, which only adds to confusion.
Even pubic health authorities aren’t immune to these discrepancies. The U.S. Department of Health and Human Services , for instance, lists 20 diseases as chronic including stroke, autism, and cancerwhile the Centers for Medicare and Medicaid Services lists 19, many of which are different from the HHS list.
Within this context, the definition can often bend to fit the situation. With the HHS, chronic is used to describe a public health concern for surveillance purposes. With the CMMS, the term broadly describes a disease for healthcare utilization purposes.
Acute Exacerbation Of Asthma
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What happens during an acute exacerbation of asthma?
Asthma is a chronic lung disease. It causes inflammation and narrowing of your airways. This can affect your airflow.
The symptoms of asthma come and go. When symptoms flare up and get progressively worse, it can be called:
- an exacerbation
- an episode
- a flare-up
Even if youve had exacerbations before and know what to do, its still a good idea to contact your doctor. An acute exacerbation of asthma is serious and can even become life-threatening. Thats why its important to recognize the symptoms early and to take appropriate action.
Its important to develop an asthma plan for how to treat your symptoms. Work with your doctor to come up with a method for what to do when your symptoms flare up.
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Is It Asthma Or Chronic Bronchitis
Chronic bronchitis is an ongoing condition characterized by a cough that occurs on most days of the month, at least three months out of the year, and lasts for at least two years. It is considered a diagnosis of exclusion meaning that your healthcare provider needs to make sure that your coughing symptoms are not being caused by another condition like asthma. Symptoms are caused by inflammation and irritation of the airways in the lung.
Prevention And Management Of Severe Asthma
Alongside taking your medication as prescribed, the best way to reduce the risk of severe asthma attacks and worsening symptoms is to avoid triggers as much as possible.
As part of your asthma management plan, its important to monitor your severe asthma symptoms. Its useful to keep a written record of your symptoms, when they occur and any triggers that may be involved. For example, your symptoms might be triggered by environmental factors, such as seasonal pollen. For women, a change in hormone levels may make things worse.
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What Makes My Symptoms Worse
Symptoms of asthma worsen with exposure to triggers. While triggers vary from person to person, worsening asthma symptoms following exposure to any of the following are more likely to indicate asthma:
- Tobacco smoke
- Some medications
Chronic bronchitis, on the other hand, is not impacted by any of these. Respiratory tract infections are more likely to cause increased symptoms.
How Do I Know If My Asthma Is Under Control
-Usually, your doctor will prescribe you medications to help control symptoms. You can also monitor this by checking the peak flow rate which measures how well your lungs are working and tells about wheeze, cough, chest tightness, or breathlessness. If all the vitals are normal, you can say your asthma is under control.
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Bronchial Challenge Test With Methacholine And Tdi
The methacholine bronchial challenge test was done according to the method previously described . Briefly, aerosols were generated by a DeVilbiss 646 nebulizer connected to a DeVilbiss dosimeter driven by compressed air . Five inhalations of normal saline at 5-min intervals were taken followed by a series of successively doubled doses of methacholine until a 20% fall in FEV1 was observed or the maximum dose given. FEV1 was measured 5-min after the beginning of each set of inhalations of aerosolized methacholine. The methacholine PC20 level was determined by interpolation from the dose-response curve. The TDI-BPT was performed according to a standardized protocol . On the first day, placebo challenge was performed for one day before the TDI challenge. On the next day, the subjects were exposed to pure TDI monomers in a small closed room for 5-15 min until asthmatic symptoms were induced and FEV1 decreased more than 20% from the baseline value. The concentration of TDI measured by TLD-1, a toxic gas detector with Cheakey was less than 20 ppb. FEV1 and FEF25-75% were measured with a spirometer immediately before exposure and every hours for 7 hr after the exposure.
Testing For Severe Asthma
Before you can be tested for severe asthma, you will need a referral from your primary healthcare asthma provider to either an asthma specialist or allergy specialist . The specialist will review your medical history, your current asthma treatment plan and do a physical exam to assess your symptoms. If the specialist thinks you may have severe asthma, they will discuss additional testing with you to determine your specific type. This often starts with testing to identify a biomarker.
Biomarkers help determine what is causing the inflammation in your airways. Taking a blood sample, analyzing a mucus sample or taking a breathing test that measure substances in your breath droplets are all common tests doctors use. These tests are performed in a doctors office or an outpatient clinic setting. Your specialist will recommend one or more of these tests based on your medical history and current symptoms. Once the biomarkers are identified, your doctor can determine the type of severe asthma and the different treatment options that are available to treat that specific type.
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Difference Between Acute And Chronic Asthma
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Asthma is a very common condition that affects people of all ages. Although there are many different symptoms and triggers, the two main types of asthma are acute and chronic. Its important to know the difference between these two types so you can take appropriate action when needed.
In short, the basic differences between acute and chronic asthma are the duration of onset & severity of symptoms. Acute asthma is more of a severe state of chronic asthma whereas chronic asthma is more of a long-term condition that stays throughout the lifespan. Both of them have their own symptoms and triggers that need to be treated on a regular basis.