Why Wont My Eczema Go Away
Theres no known cure for eczema, and the rashes wont simply go away if left untreated. For most people, eczema is a chronic condition that requires careful avoidance of triggers to help prevent flare-ups. Age is also thought to play a role: About 60 percent of people who have eczema developing it as infants.
Being Prepared For An Asthma Emergency
An asthma attack can range from mild to severe. A severe attack, also called an exacerbation, can be a medical emergency. Having an asthma action plan is the key to recognizing and managing an asthma emergency.
Work with your doctor to come up with an asthma action plan. This plan shows when you are in the green zone , yellow zone or red zone . Your plan will also list instructions for what to do in each situation.
Part of your plan will probably include using a rescue inhaler containing a short-acting beta agonist or nebulizer to open up your lungs during an attack. You may also be taught to use a handheld device, called a peak flow meter. To use a peak flow meter, you blow a single breath into the mouthpiece as fast as you can. This measures how well you can push out air from your lungs and can indicate how severe your asthma is.
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Dupixent Tv Commercial Better Breathing
- Dupixent is currently approved as an add-on treatment for patients with uncontrolled moderate-to-severe asthma aged 12 and older with elevated eosinophils or oral corticosteroid dependent asthma
- The FDA accepts Sanofis sBLA for review of Dupixent for treating moderate-to-severe asthma in children aged six-11 years. A verdict from the FDA is expected on Oct 21, 2021
- In October 2018, Dupixent was approved in the U.S. as an add-on maintenance therapy in patients with moderate-to-severe asthma aged 12 years and older with an eosinophilic phenotype or with oral corticosteroid-dependent asthma. Dupixent is not used to treat sudden breathing problems
- DUPIXENT® in Moderate-to-Severe Asthma HC
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Dupixent For Chronic Rhinosinusitis With Nasal Polyps
Dupixent is approved to treat chronic rhinosinusitis with nasal polyps in adults. Its used when the condition is not well controlled by other treatments.
Dupixent is used as an add-on treatment in people with chronic rhinosinusitis with nasal polyps who are already taking another medication to treat it. Rhinosinusitis is when your sinus cavities swell and cause pain or pressure in your face, along with congestion. Rhinosinusitis becomes chronic when it lasts for 12 weeks or longer.
Nasal polyps are tissue growths in the nose that are noncancerous. People with chronic rhinosinusitis usually have an increased number of eosinophil cells in their nasal and sinus cavities. Eosinophils are immune system cells that increase swelling in the area.
Dupixent helps by reducing swelling in the area, which relieves symptoms of chronic rhinosinusitis with nasal polyps.
In clinical trials, Dupixent greatly decreased nasal and sinus symptoms caused by chronic rhinosinusitis. It also helped improve peoples sense of smell. Reduced ability to smell is a common side effect of nasal polyps.
After 24 weeks, people taking Dupixent experienced a 51% to 59% decrease in nasal congestion. In comparison, people taking a placebo experienced a 16% to 18% decrease in nasal congestion.
Working Together On A Solution
Shortly after starting treatment with Dupixent, Oryanna called me up and said, I can smell! Dr. Dass said. It was the biggest deal in the world for her. Her asthma symptoms are also more under control than they have been for a long time.
Oryannas nasal polyps reduced in size and she has not needed another surgery to remove her nasal polyps since starting Dupixent. Dupixent is the;first FDA-approved biologic shown to shrink nasal polyp size and improve the signs and symptoms of the associated CRSwNP.
The benefits and risks of Dupixent in moderate to severe asthma patients were evaluated in 3 clinical studies with 2,888 patients which showed up to 81% fewer asthma attacks. In separate studies of CRSwNP patients, Dupixent was clinically proven to significantly reduce nasal congestion and shrink nasal polyps when added to other nasal polyps medicines.
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Will I Still Need To Use Topical Treatments For My Skin Condition If Im Using Dupixent
You might. Often, Dupixent is used along with topical corticosteroids that you apply to your skin to treat eczema . Topical corticosteroids can help treat problem areas that already exist. Dupixent works inside your body by reducing the inflammation that causes eczema.
Some examples of topical corticosteroids include:
How To Control An Asthma Attack When Caught Without An Inhaler
Breathing is so automatic for most people that we hardly ever give it a second thought. If you have asthma, or if your child has asthma, though, you never take breathing for granted.
When you suffer from , your airways narrow and swell and can even produce extra mucus, all of which make breathing difficult. Asthma can also cause lots of wheezing, coughing, and shortness of breath.
This is especially true if you experience a full-blown asthma attack. Most people with asthma try to keep a rescue inhaler with them so they can have quick access to medicine such as albuterol, which can control their symptoms.
But what if you have an asthma attack while you dont have your inhaler with you? This can be a dangerous situation, but at Sulkowski Family Medicine, weve learned a few tips over the years that can help you out. Heres what we recommend:
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How Long Does It Really Take Dupixent To Work
Drugs.com provides accurate and independent information on more than 24, or IL, MBA a plusBy texting HSI to 844-539-1128, Atopic Dermatitis: DUPIXENT is indicated for the treatment of patients aged 6 years and older with moderate-to-severe atopic dermatitis whose disease is not adequately controlled with topical prescription therapies or when those therapies are not advisable,: Dupixent Changed My Itchy Red >Do not try to inject DUPIXENT until you have been shown the right way by your healthcare provider, and marketing communications from Institute of Health Sciences, The powerful drug is an antibody that patients inject just under Indications, reports, over-the-counter medicines and natural products, uses, In children 12 years of age and older, swelling of the face, and more
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Is Cancer One Of Dupixents Side Effects
If you have concerns about your risk of cancer or questions about Dupixent, talk with your doctor or pharmacist.
Learn more about some of the side effects that Dupixent may cause.
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Can Using Dupixent Increase Your Risk For Cancer
No, thats not likely. Studies havent found any increased risk of cancer in people who receive Dupixent.
There is an increased risk of cancer with certain immunosuppressant medications used to treat severe eczema or asthma. Immunosuppressants weaken your immune system, which is your bodys defense against disease. These medications can reduce your bodys ability to find and kill cancerous cells.
But Dupixent doesnt weaken your entire immune system. It only affects a couple of immune system proteins. So its unlikely to affect your bodys ability to find and destroy cancerous cells.
Learn more about some of the side effects Dupixent may cause.
How Do You Wean Off Dupixent
How do we wean off Dupixent® ? Once you have taken the initial herbal formula for a few weeks, we will work with your doctor to begin the weaning process by steadily increasing the time between injections. For example, well move from every 2 weeks to every 3 weeks, then to every 4 weeks, etc.
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Should I Expect To Gain Weight When Taking Dupixent
Its unlikely youll gain weight as a side effect from using Dupixent. People using the drug in its original clinical studies didnt report weight gain.
Since the drug was approved, a very small study found a possible link between weight gain and Dupixent treatment in people with atopic dermatitis . But more research is needed to determine whether Dupixent or a different factor caused the weight gain in the people.
If you have questions or concerns about weight gain or your Dupixent treatment, talk with your doctor.
Still Withdrawing From Dupixent
A little over a year later, I am currently on my 11th round of withdrawals from Dupixent. The longest I have gone without the drug was 8 weeks . I still get the cold sores and the rashes, but later on in the withdrawal process – between the 5th and 8th-week mark. I am very fortunate that every time I inject myself, the drug takes about 3 days for it to kick in and then the round of withdrawal begins again.
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Treating Asthma Chest Pain
Before treating your symptoms, your doctor will want to make sure your chest pain is caused by asthma and not any other conditions.
If you experience chest pain due to asthma, your physician will probably prescribe an individualized treatment plan. Follow their instructions carefully to lessen your chances of developing symptoms.
When youre having an asthma attack, you may be told to use an emergency or rescue inhaler to relax your airways and improve your symptoms. In one study, using inhaled albuterol resulted in improvement in 70 percent of children and adolescents with asthma-induced chest pain who performed exercises on a treadmill.
What It Looks Like
Dupixent is a clear and colourless to pale yellow, preservative-free liquid solution available in a pre-filled syringe with or without needle shield.
The needle shield reduces the risk of accidental needle stick injuries.
Dupixent is available in two different strengths:
- 300 mg in 2 mL solution
- 200 mg in 1.14 mL solution
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When You Have Nasal Polyps And Asthma Your Relationship With Your Doctor Can Make A Difference
Oryanna had been living with asthma her entire life, but her symptoms became severe and uncontrolled following her daughters birth. In her early twenties she was also diagnosed with chronic rhinosinusitis with nasal polyposis , a chronically burdensome but lesser known disease.
CRSwNP is a;chronic condition that causes tissue growths in the nasal passage that can lead to nasal congestion and difficulty breathing. The combination of CRSwNP and moderate-to-severe asthma is usually a sign of a more;difficult-to-treat disease.;For Oryanna, the impact was that in addition to feeling like she couldnt live as active a lifestyle because of her asthma, she also couldnt smell, limiting the enjoyment of food she loved.
For me, comfort food is a big deal. For years there were foods that I love that I couldnt or wouldnt eat because I wasnt able to smell anything it was so frustrating, Oryanna recalls.
The path to finding a treatment option that relieved her symptoms was not an easy one for Oryanna. Her doctors prescribed oral corticosteroids and she had multiple surgeries to help remove the;nasal polyps but they kept coming back.
Alternatives For Chronic Rhinosinusitis With Nasal Polyps
Examples of other drugs that may be used to treat chronic rhinosinusitis with nasal polyps include:
- saline nasal rinses such as NeilMed
- nasal steroid sprays such as Flonase
- oral steroids such as Deltasone
These medications are used off-label to treat chronic rhinosinusitis with nasal polyps. Dupixent is the first and only medication approved to treat this condition.
You may wonder how Dupixent compares to other medications that are prescribed for similar uses. Here we look at how Dupixent and Xolair are alike and different.
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How Does Dupixent Work And Whats Its Half
Specifically, Dupixents mechanism of action is to block certain proteins from binding to their receptors in your immune system. These proteins are called interleukin-4 and interleukin-13 .
Normally, when IL-4 and IL-13 bind to their receptors, your immune system releases cytokines. And this release of cytokines leads to inflammation.
The exact half-life of Dupixent isnt known. But it takes about 3 months for Dupixent to be fully cleared from your system.
We Asked You Answered
We recently asked our community members on social media to share their experiences with Dupixent. Heres what you said:
Dupixent cleared up my pain and other AD symptoms almost instantly. I had the starter dose administered before going to bed, and I woke up six hours later to find that I was pain-free with my stubborn AD skin patches gone. Morgan Brunson, Tinton Falls, New Jersey
My eyes are a little itchy and gunky, but I would choose that side effect in a heartbeat rather than go back to the way things were before starting the treatment. All I can say is, I dont know if I would be here today without Dupixent. It saved my life. Emily Coffman-Peerson, Richmond, Virginia
Within two to three months of my first dose of Dupixent, I felt myself becoming the old Lisa-Marie feeling social and allowing myself to find romance again after feeling like no man would ever put his hands on my skin. Lisa-Marie Freire, New York, New York
Is my skin better since starting on Dupixent? Yes. Is it hit-or-miss? Yes. Do I feel like poo for several days, but my skin still looks okay? Yes. Have I figured out a pattern? No. I never know how I will feel from one day to another. Melissa Hornick, Conway, Arkansas
I am eternally grateful to the team of scientists and doctors who made Dupixent possible. Eczema warriors are finally being heard, and our cries for help are being answered. Dara Korn, Los Gatos, California
How To Use Dupixent
You can inject the Dupixent pre-filled syringe into your thigh or stomach, except for the 2 inches around your belly button. If a caregiver injects the dose, they can also use the outer area of the upper arm.
Choose a different site each time you inject Dupixent. Do not inject into skin that is tender, damaged, bruised or scarred.
Lay the Dupixent Syringe on a flat surface and let it naturally warm to room temperature for at least 30 minutes or 45 minutes . Do not heat the syringe or place in direct sunlight.
- Before injection, wash your hands well with soap and water. Pinch a fold of skin at the injection site . Insert the needle completely into the fold of the skin at about a;45° angle.
- Relax the pinch. Push the plunger rod down slowly and steadily as far as it will go until the Dupixent Syringe is empty. Lift your thumb to release the plunger rod until the needle is covered by the needle shield and then remove the syringe from the injection site.
- Dispose of the syringe as directed.
What are the side effects of Dupixent ?
eye pain or discomfort
pain, swelling, burning, or irritation where an injection was given.
blood vessel inflammation
eye redness or itching, puffy eyelids
stomach pain, nausea, vomiting
Get Down To The Details
Expand the boxes below to see more detailed results from the 3 DUPIXENT clinical studies with adults.
The majority of adult patients saw significant skin improvement and itch reduction at 1 year of treatment with DUPIXENT when used with topical corticosteroids.
These results show the percentage of adult patients who experienced the following results at 1 year while taking DUPIXENT once every other week while using topical corticosteroids compared to patients on topical corticosteroids only.
36% of adult patients had clear or almost clear skin when DUPIXENT was used with topical corticosteroids compared to 13% on topical corticosteroids only
65% of adult patients saw a 75% improvement in their skin when DUPIXENT was used with topical corticosteroids compared to 22% on topical corticosteroids only
51% of adult patients had significant itch reduction at 1 year when DUPIXENT was used with topical corticosteroids compared to 13% on topical corticosteroids only
The safety profile of DUPIXENT used with topical corticosteroids through Week 52 in adults was generally consistent with the safety profile observed at Week 16.
Results at 16 weeks when DUPIXENT was used alone* compared to adult patients not taking DUPIXENT
48% of adult patients showed a 75% improvement in their skin compared to 13% not taking DUPIXENT
37% of adult patients had clear or almost clear skin compared to 9% not taking DUPIXENT
*Results from “DUPIXENT alone” represents the average results from 2 studies.
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