Connecting The Dots At The Cellular Level
Because study participants also revisit the pulmonary laboratory for another round of collecting cells and lung fluid as well as blood samples, theres a treasure trove of material to analyze at the cellular and molecular level. Stephane Esnault, a senior scientist in the Busse laboratory, is conducting a battery of tests including PCR and ELISA assays to quantify how much inflammation is occurring in lung cells and tissue.
The project also involves RNA-seq, a molecular technique to identify which genes are expressed in a sample. RNA-seq will help us find new molecular pathways involved in this process that we don’t know about yet. It’s very exploratory, said Esnault. Altogether, these components of the study will involve a tremendous amount of number-crunching. The biostatistician is going to have a lot of work, laughed Esnault.
Tips For Reducing Stress At Bedtime
Occasional stress at bedtime is inevitable. Having a plan for coping with stress can help you prevent stress from interfering with your sleep. Here are tips for learning to recognize the signs of stress and combating stress at bedtime:
Although stress can certainly interfere with getting a good nights sleep, it doesnt have to take control of your life. Understanding the bodys stress response and making a plan for managing stress can help you regain control and improve your rest.
The Normal Respiratory System
To understand what happens in asthma you need to be familiar with the normal breathing system and how the lungs and airways are arranged.
Normally, air entering through the mouth and nose travels through the main airway through a series of smaller branching airways called bronchi. The bronchi divide up into even smaller airways called bronchioles, which end in millions of tiny air sacs called alveoli.
When air enters the alveoli, the oxygen it contains passes through the thin membrane covering each sac into surrounding blood vessels. The oxygen attaches itself to red blood cells which then circulate around the body, releasing the oxygen into the body tissues.
What happens during an asthma attack?
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Stress Effects On The Body
Stress affects all systems of the body including the musculoskeletal, respiratory, cardiovascular, endocrine, gastrointestinal, nervous, and reproductive systems.
Stress effects on the body.
Our bodies are well equipped to handle stress in small doses, but when that stress becomes long-term or chronic, it can have serious effects on your body.
When the body is stressed, muscles tense up. Muscle tension is almost a reflex reaction to stressthe bodys way of guarding against injury and pain.
With sudden onset stress, the muscles tense up all at once, and then release their tension when the stress passes. causes the muscles in the body to be in a more or less constant state of guardedness. When muscles are taut and tense for long periods of time, this may trigger other reactions of the body and even promote stress-related disorders.
For example, both tension-type headache and migraine headache are associated with chronic muscle tension in the area of the shoulders, neck and head. Musculoskeletal pain in the low back and upper extremities has also been linked to stress, especially job stress.
Relaxation techniques and other stress-relieving activities and therapies have been shown to effectively reduce muscle tension, decrease the incidence of certain stress-related disorders, such as headache, and increase a sense of well-being. For those who develop chronic pain conditions, stress-relieving activities have been shown to improve mood and daily function.
Can I Use An Inhaler For Anxiety
While it may not be a primary method for dealing with anxiety, using a rescue inhaler is an option for dealing with an anxiety attack. Talk with your doctor before doing so.
What is Aluna?
Aluna is an innovative, scientifically-accurate, and portable spirometer cleared by the FDA.
This device and management program is designed to help adults and children, 5 years and up, monitor their lung function and take control of their respiratory health.
Aluna automatically tracks your FEV1% over time. You can also monitor your symptoms, medication, exercise, and environmental factors.
With the Aluna app, you can easily
Aluna is seeking to shed light on asthma and other lung diseases by providing accurate and reliable data for healthcare providers and patients.
Be sure to ask your healthcare professional about Aluna and how this device can benefit you.
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Research For Your Health
The NHLBI is part of the U.S. Department of Health and Human Services National Institutes of Health the Nations biomedical research agency that makes important scientific discovery to improve health and save lives. We are committed to advancing science and translating discoveries into clinical practice to promote the prevention and treatment of heart, lung, blood, and sleep disorders, including asthma. Learn about the current and future NHLBI efforts to improve health through research and scientific discovery.
Psychological Interventions Aimed At Improving Adherence And Asthma Control
A number of studies have examined the efficacy of psychological therapies at improving various aspects of asthma control or quality of life. These studies have been reviewed for both adults and children and are not discussed in detail here. Because psychotherapy models can be grouped according to their theoretical frameworks or methods of operation, the various approaches are briefly discussed below:
1. Behavioural therapies focus on identifying the processes by which behaviour has been learned via association, reward, or observation and modifying behaviour using methods such as systematic desensitization, selective reinforcement, and positive modeling. The behaviour itself, rather than the underlying motivations, is the focus of behavioural interventions. Dahl found positive results following behavioural therapy when school absenteeism and use of as-needed medications were the outcome measures .
2. Cognitive therapies focus on identification and constructive management of incorrect and damaging thoughts, such as perceptions of helplessness or inappropriate fear of asthma attack, that can trigger episodes. Information also targets cognitions.
5. Psychodynamic psychotherapies attempt to uncover the emotional issues and response styles that drive patients to behave in maladaptive ways. Controlled trials of dynamic therapy are infrequent, and there is little evidence that they are likely to be of utility in a significant number of patients with asthma.
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How To Manage Stress And Asthma
Have An Effective Treatment Plan
People with well-managed asthma should experience few symptoms and be able to enjoy their day-to-day lives with ease. If, however, your asthma is unmanaged, you may experience severe symptoms and an increased chance of having an asthma attack. If you notice an increase in your symptoms severity or require your reliever medication more frequently, you must make an appointment with your healthcare provider to discuss it further.
How To Manage Stress With Asthma
Stress is part of daily life — with or without asthma. That’s why it’s important to find effective ways to manage stress if you do have the disorder. Learning to relax before you feel stressed can help you prevent shortness of breath and avoid an asthma attack.
Change Your Thoughts. Learn to change thought patterns that produce stress. What you think, how you think, what you expect, and what you tell yourself often determine how you feel and how well you manage rising stress levels.
Reduce Your Stressors. Identify the major stressors in your life such as money problems, relationship problems, grief, too many deadlines, and lack of support. If you can’t resolve these stressors alone, get professional help.
Avoid Stressful Situations. Try to avoid situations that trigger stress for you. Practice effective time-management skills, such as delegating when appropriate, setting priorities, pacing yourself, and taking time out for yourself.
Get Plenty of Sleep. With asthma or any chronic illness, you need plenty of sleep. If you are not sleeping well or suffer with nighttime asthma, you will have less energy and fewer resources for coping with stress. Developing good sleep habits is very important. Here are seven sleep tips:
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Is All Stress Unhealthy
While we generally think of stress as a bad thing, not all stress is unhealthy. It is often what drives us to succeed and get things done. How we deal with stress is very personal. Some people need tight deadlines to get their best work done, while others need to plan everything well in advance. Going after a promotion at work or trying to meet new people can be stressful, but the benefits can lead to excitement and rewards that far outweigh the stress. Just knowing how you deal with the everyday stresses of getting stuff done may be important for you to manage the stresses of everyday life.
Yes, some levels of stress can a good thing. But chronic stress, on the other hand, is not good for you or your asthma. It can come from many different sources and can impact your immune system and impact your health and your asthma. Stress causes our bodies to release the hormone cortisol chronic elevation of cortisol can have cause inflammation.
Stress also impacts our regular routines- like taking medication. If you are stressed out about school or work you might forget to take your controller medication or walk out of the house without your rescue inhaler. Both situations potentially put you at risk for a worsening of your asthma symptoms.
What Is Asthma & What Causes An Attack
Asthma is a condition that affects more than 22 million Americans, making it one of the most common chronic conditionsespecially in children. Affecting the respiratory system, asthma causes the airways to inflame and swell, making breathing extremely difficult. While asthma is only a minor issue for some, it can be a major health concern for othersinterfering with daily routines and potentially leading to life-threatening asthma exacerbations. An asthma attack can be triggered by a wide range of irritants, including:
- Pollution and other environmental stressors
Because these irritants vary so vastly from person to person, understanding your specific triggers can help you control your conditions and avoid exacerbations.
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Researchers Investigate How A Stressed Brain Can Make Asthma Worse
William Busse, a professor of asthma, pulmonary and critical care medicine at the UWMadison School of Medicine and Public Health, is looking at connections between the immune system and the brain. Clint Thayer/Department of Medicine
Researchers at the University of WisconsinMadison are investigating cross-talk between the brain and lungs of people with asthma in a four-year, $2.5 million study to understand how psychological stress can make asthma symptoms worse.
Through a clinical study called AsthMatic Inflammation and Neurocircuitry Activation, or MINA, the team hopes to decipher exactly how mind and body connect when people with asthma experience stress and find ways to alter brain-lung communication to help them manage their disease.
The effort is led by two groups with international reputations in the two areas united by the study: a team led by William Busse, a professor of asthma, pulmonary and critical care medicine at the UWMadison School of Medicine and Public Health and a team headed by Richard Davidson, William James and Vilas Professor of Psychology and Psychiatry at the UW-Madison Center for Healthy Minds.
A project 20 years in the making
The new study represents a partnership between Busse and Davidson that extends back to 1995, when the pair participated in a scientific meeting focused on how stress may alter a persons susceptibility to worsening asthma.
What Is The Respiratory System
The respiratory system is the network of organs and tissues that help you breathe. It includes your airways, lungs and blood vessels. The muscles that power your lungs are also part of the respiratory system. These parts work together to move oxygen throughout the body and clean out waste gases like carbon dioxide.
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Does Asthma Cause Permanent Damage
The airway obstruction of asthma is generally completely reversible and usually does not cause permanent damage to the lungs, heart, or other organs. However, severe acute episodes of asthma can be associated with life threatening events and even fatalities. Survival of severe life threatening events can be associated with damage from lack of oxygen during the severe exacerbation, and lack of oxygen to the brain can cause loss of consciousness and brain damage.
Chronic asthma with ongoing airway inflammation may also be associated with what is called remodeling of the airways. This describes permanent changes occurring in the tissues surrounding the airways that results in permanent narrowing of airways. The potential for this emphasizes the importance of monitoring pulmonary function in patients with asthma at regular intervals, particularly those with a chronic pattern of asthma.
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How To Manage Asthma
Know what makes your asthma worse and avoid them. The triggers may include:
- Certain health conditions such as colds, flu, or acid reflux
- Allergies to food or medicines
- Cigarette smoke
- Pollen from grass, weeds, flowers or trees
- Extreme temperatures and high humidity
- Air pollution
- Cockroaches, rodents or dust mites
- Dander or saliva from pets
- Strong odors
2. Understand Your Peak Flow and Monitor It
Your peak flow tells you how open the airways are when you exhale and this can be measured using a peak flow meter. Use this device to track the severity of you asthma or to monitor the progress of your treatment. This will help your doctor adjust your treatments. Your best or highest peak flow rate can occur over a few weeks of proper treatment. Evaluate your response to treatment by comparing your day-by-day peak flow rate with your best reading.
3. Treat Asthma
After the answer to “how does asthma affect the body?” here are also treatment options for asthma. There is no cure for asthma, but medicines can help improve most of your symptoms. Long-acting medications or controller medicines reduce swelling of the airways and mucus production. They help prevent asthma attacks. These medicines include corticosteroids which help reduce inflammation. They are often used daily as your doctor prescribes, even when you are not sick. Some examples of long-acting medicines to control symptoms are:
5. Live a Healthy Life
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How Do I Know If Stress Is Triggering My Asthma Symptoms
The first step is knowing that youre under stress sometimes we dont recognise the signs. Stress can make you feel more irritable, tired, more worried than usual. You might feel teary, restless or find it hard to make decisions.
The second is understanding that stress levels can make your asthma worse sometimes we dont make the connection between stressful events and our asthma symptoms.
To see if stress might be triggering your asthma symptoms try keeping a diary write down when and why youre stressed alongside any asthma symptoms.
You might start noticing patterns. For example, perhaps you got asthma symptoms more when you were moving to a new house, or your asthma seemed worse when you had exams coming up.
A written asthma action plan helps you keep an eye on symptoms getting worse and reminds you what to do if you notice any.
How To Keep Your Anxiety Under Control
Again, while anxiety cannot cause a patient to develop asthma, living with asthma can cause anxiety. Health concerns are a common trigger for some anxiety cases. A patient put through the shock of an asthma attack, especially when it results in hospitalization, could easily develop an anxiety disorder from living in chronic fear. This anxiety, in turn, exacerbates the asthma symptoms, which triggers intensified anxiety, and so on.
If this is the case, the best method of treatment is to do everything you can to relieve the anxiety symptoms before they become a problem. Anxiety like pollen, dust, or mold is an asthmatic trigger, and needs to be treated like one. When you anticipate an anxious situation arising, try calming exercises to stem the anxiety. Or if you suspect something may lead to anxiety in the future, take preventative measures or avoid the situation altogether.
Try some of these stress-reduction techniques to keep calm under pressure:
Meditate: Gift yourself a moment of peace. Take a deep breath, and clear your mind of stressful thoughts. Focus on being present, and savor the physical sounds and sensations surrounding you. Meditation, and the art of being present, is a proven relaxation technique to calm the mind and body.
If your anxiety symptoms are severe, consult a trained medical professional for therapy and medication. Remember that asthma always requires medical treatment and specialized attention.
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Asthma Causes And Triggers
When you have asthma, your airways react to things in the world around you. Doctors call these asthma triggers. They might cause symptoms or make them worse. Common asthma triggers include:
- Infections like sinusitis, colds, and the flu
- Allergens such as pollens, mold, pet dander, and dust mites
- Irritants like strong odors from perfumes or cleaning solutions
- Air pollution
- Strong emotions such as anxiety, laughter, sadness, or stress
- Medications such as aspirin
- Food preservatives called sulfites, found in things like shrimp, pickles, beer and wine, dried fruits, and bottled lemon and lime juices
Stress Test And Cortisol Collection At Age 16 Years
At age 16 years, 715 adolescents performed a stress test, based on the Trier Social Stress Task . The stress test consisted of two parts. In the first part, the adolescents were instructed to prepare a 6-min speech about themselves and their lives and deliver this speech in front of a video camera. The speech was followed by a 3-min interlude in which the adolescents were not allowed to speak. In the second part, adolescents were asked to perform a 6-min mental arithmetic task. The adolescents were instructed to repeatedly subtract the number 17 from a larger sum, starting with 13 287. The mental arithmetic task was followed by a 3-min period of silence, after which the adolescents were debriefed about the experiment. Adolescents with a high risk of mental health problems were over-represented in this population .
Cortisol was assessed from saliva collected prior to the stress test , directly after , and 20 minutes and 40 minutes after the stress test . Non-responders did not differ from responders in terms of sex non-responders were slightly older .
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