Age Related Changes In Hepatic And Extrahepatic Drug Biotransformations
There is some suggestion that Phase I biotransformations catalyzed by CYP2C are decreased with age, with modest decreases in clearance of warfarin and phenytoin reported in older individuals. However, this is much less well established . Similarly, Phase I biotransformation by CYP1A2 may be somewhat decreased in older individuals, and decreased theophylline and caffeine clearances have been reported . However, this too is not well established.
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10 House Plants Safe For Asthma and other Allergies
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How I Treated My Asthma Naturally & Why I’ll Never Use An Inhaler Again
I will not use my inhaler ever again! Thats what I said to myself a year after I was diagnosed with asthma in 2010. In the summer of 2011, I decided to make a career and lifestyle change and enrolled in a health coaching program to learn more about nutrition. During that time, I did extensive research on asthma, some of the causes, side effects and if there were any cures. Based on my personal research, here are the steps I decided to take.
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Can Asthma Be Cured What Are The Latest Treatments
- May 3, 1999
Javeed Akhter, M.D., Section Head of Pediatric Pulmonology at Hope Children’s Hospital in Oak Lawn, Ill., offers the following answer:
| Image: STEVE KAGAN, M.D.MAST CELL. These large cells, filled with potent inflammation-inducing chemicals called leukotrienes, line the respiratory tract and play a central role in allergy-induced asthma. |
Asthma is an eminently controllable illness. Indeed, for most sufferers, control is so effective that it amounts to a virtual cure. But asthma is not curable in the same way as, say, a bacterial pneumonia; it never entirely goes away. Also, no one cure would ever suffice. It is becoming increasingly clear that there many types of asthma–and they differ greatly in their presentation and genesis. For example, asthma that presents as a chronic cough, the “cough variant of asthma,” appears to be very different from the life-threatening variety, which results in extreme respiratory failure and sometimes death.
Another effective strategy for preventing inflammation is the use of certain medications either daily during a season , during multiple seasons or year-round. One class of these medications stabilizes the mast cell, , which line the respiratory tract and play a central role in allergy-induced asthma. These mast cell-stabilizing inhalants include Cromolyn and Nedocromyl. Cromolyn is of particular interest as it is derived from the plant Ammi Visnaga, long used by American Indians as an herbal remedy for colic.
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Special Considerations For Altitude Travel
Asthma Although theoretically the cold, dry, hypoxic mountain environment should worsen bronchoconstriction, there is little evidence of deterioration in practice. Asthmatics often find that they have less trouble at high altitude and this is likely to be related to the absence of allergens in the air and the reduced air density. They may also be helped by the increased sympathetic drive and production of corticosteroids at altitude. Patients should not ascend to altitude unless their asthma is stable. Travellers to remote places should take an emergency supply of steroids with them in case of deterioration.
What Causes Dust Allergy
Dust mites are the main culprits behind dust allergy. Listed below are a few other causes:;
- Pollen Pollen is a fine powdery substance that consists of pollen grains. It is a natural part of trees, flowers, and grasses. Different people may be allergic to different types of pollen.
- Cockroaches Cockroach droppings can cause dust allergy in some individuals when inhaled . These tiny particles often combine with household dust to cause allergy.
- Mold Mold is a kind of fungus that has spores that are capable of floating in the air. These spores can also cause dust allergy .
- Yeast Yeast is a cousin of mold, and you can have an overgrowth of yeast called Candida albicans in your intestines due to the overuse of antibiotics. Yeast can also colonize your nasal mucous membranes and sinuses, making them irritated and susceptible to dust allergies .
- Animal Hair, Fur, And Feathers Pets are another cause of dust allergy . Their skin flakes , urine, or saliva are potential allergens, especially when combined with dust.
Dust allergy is often accompanied by non-stop sneezing and cold-like symptoms. The signs and symptoms are discussed below.
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So Can Asthma Be Cured Completely
Asthma cannot be cured completely, no, but it can be controlled to the point that the symptoms become negligible. As a chronic and lasting condition, asthma is not curable. It is highly treatable, though, so long as a patient has professional support.
Many doctors believe there are actually different kinds of asthma with their own causes. Its true that different patients have different triggers for their asthma, as well as different responses, so its likely that there are different causes and thus different treatments for asthma. Here at Allergy & Asthma Center, we can address asthma in a number of ways to alleviate our patients symptoms, sometimes almost entirely.
Nonprescription Drugs And Nutritional Supplements
Nonprescription medicines are important aspects of medications use for a number of reasons. First, OTC status is not limited to the safest drugs available. An international comparison of which medicines are available without a prescription in various nations of the industrialized world shows that legal, ethical, and political considerations may be as important as safety data. For example, asthma is a dangerous, non-self-limiting disease that requires medical attention. Epinephrine, a potent drug, was approved by the FDA in 1939. Most epinephrine products are prescription-only. However, epinephrine administered by a metered-dose inhaler is available without a prescription for treatment of asthma.
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Make An Asthma Action Plan
If you don’t have one already, work with your doctor to create an asthma action plan. This is something you talk about and write down. It helps you tell how well-controlled your asthma is and what to do about it. Your action plan might include:
- How much medicine to take and when
- A list of your triggers and ways to avoid them
- What to do when you have specific symptoms of trouble
What Causes The Link Between Gerd And Asthma
The mechanisms behind the association arent crystal-clear, but there are a few theories. One is that if someone has GERD, aspiration of stomach acid into the airways can cause irritation there, leading to breathing difficulties or a persistent cough.
If you have acid reflux and you regurgitate high enough, you can get a bronchospasm that can trigger asthma, Dr. Vaezi notes. Another theory is that acid reflux may trigger a protective nerve reflex that causes the airways to tighten in order to prevent the stomach acid from entering the lungs; this can lead to a bronchospasm;too.
There isnt a single test that can definitively identify reflux as the cause of asthma-like symptoms in those with GERD. But not responding to steroids is a big red flag to consider GERD in a patient with severe asthma, notes;Kaiser Lim, MD, a consultant in pulmonary and critical care medicine at the Mayo Clinic in Rochester, Minnesota. To determine if reflux is exacerbating asthma, doctors typically consider a persons symptoms and their response to treatment. In terms of treatment, a doctor might prescribe aggressive use of acid-suppressing medication to see if the asthma-like symptoms improve, Vaezi says.
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Yoga And Practising Mindfulness
The benefits of yoga are manifold. If you want to get relief from your asthma symptoms, make sure you do yoga every single day. Yoga incorporates breathing and stretching exercises. It will help to increase your flexibility and also boost your overall fitness. Some yoga poses that can help open your throat and chest are the bound angle pose, bow pose, bridge pose, camel pose, cat pose, cobra pose, cow pose, and cat pose among many others. Meditate every day and increase focus on your mind and body. The focus on breath and stress control from yoga and meditation will help you a lot in breathing easily.
Also Read:;Health Benefits of Meditation
Homeopathy Medicine For Asthma
Homeopathy treatment shows a positive result for bronchial asthma and it is safe in the case of children who are suffering from this condition. Homeopathic remedy reduces asthma medication in children. In the case of the tolerance factor, homeopathy is well enough to fight against allergens like pollen grain, dust, pollutants, etc. Some of the homeopathy treatments and homeopathy remedies are given below
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I Identified My Asthma Triggers
No one really knows what causes asthma, but its important to know some of the triggers and what to avoid. In my case, the cause is still unknown as I didnt get asthma until I hit my 40s.
I became aware of my shortness of breath immediately after eating or drinking certain things like desserts, wine, peanuts and cheese. Consuming these items can trigger your asthma, in addition to other items such as:
- Eggs
- Food coloring
- Desserts
Asthma can also be brought on by exercise, smoking, allergies, pet dander, dust mites, and even stress. Shortness of breath, wheezing and tightness of the chest are some of the symptoms among people with asthma.
Its important to not diagnose yourself, but to seek medical advice with any type of physical discomfort.
/8home Remedies For Treating Asthma Naturally
Are you looking for some natural home remedies to keep asthma at bay? Asthma can be a life threatening condition. It is a lung disease that causes difficult breathing. It is triggered by infections, emotions, weather conditions, pollution and certain medications. Common symptoms include coughing, wheezing, shortness of breath and chest tightness. You will be surprised to know some ingredients in your kitchen can help you keep those asthma attacks at bay.For example, honey is one the oldest natural remedies to treat asthma.Before going to bed, swallow one teaspoon of honey with a pinch of cinnamon powder. It will help in removing phlegm from the throat and allow you to sleep better. Squeeze the juice of half a lemon in a glass of water and add some sugar according to your taste. Drink this regularly to reduce asthma attacks.Drinking coffee is the easiest and the most effective way to treat asthma. A hot cup of coffee helps in relaxing and clearing the airways and helps to breathe easily.Boil 3-4 cloves of garlic in half a cup of milk. Allow it to cool at room temperature and then drink it. It helps in clearing congestion in the lungs during the early stages of asthma. Here is the list of natural remedies that you can use to get relief from asthma and its symptoms.
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Familial Strengths And Resilience
As discussed in Chapter 2, the available evidence suggests that schizophrenia and other major mental illnesses, like many other biologically caused disorders such as asthma or hypertension, have a large genetic component. Persons with this genetic component are often vulnerable to environmental stresses or triggers that promote specific biological events, such as changes in neurotransmitter functioning. Some aspects of family life may cause stress, which in turn may trigger relapse or the recurrence of symptoms. In any case, families are neither a necessary nor sufficient cause of serious mental illness.
Basophils are the least abundant leucocytes, accounting for less than 0.5 of bone marrow and peripheral blood leucocytes. Basophils arise from a common basophil-eosinophil progenitor cell, mature in the marrow over a period of 2-7 days and after release in the circulation last for up to 2 weeks. They are the key mediators of immediate hypersensitivity reactions such as asthma, urticaria and anaphylaxis. In addition, they have been implicated in delayed cutaneous hypersensitivity reaction. Basophils are stimulated by a number of mediators, such as IgE, IL-3, C5a, GM-CSF, insect venoms and morphine, to release the contents of their granules such as histamine.
The Bottom Line: Are Natural Remedies Safe For People With Asthma
Peters points out that just because studies havent established a definite benefit doesnt mean that some of these wont help some people. Each individual may react differently, and what works for some people with asthma may not work for others. But until many of these complementary and alternative options have stronger scientific evidence to back up their role, they cant be recommended on a large scale to people with asthma, says Hill.
So, if you see something marketed as a natural remedy for asthma, approach it with caution, and dont make changes to your asthma action plan without discussing it with your doctor first.
Additional reporting by Moira Lawler and Christina Vogt.
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Ayurveda For Asthma Treatment
Due to modern faulty lifestyle, uncontrolled pollution, and rapid industrialization, allergy, allergens, bronchial asthma has become common among children, adult,s and aged people. Ayurvedic herbal supplements, natural remedies, and dietary treatments are good for the disorder. This disease comes in the paroxysm of dyspnoea and during the attack; the patient goes in extreme agony, perceives darkness, feels thirst, and becomes motionless. On account of frequent coughing and expectorant, the patient faints and remains in extreme distress till phlegm is coughed out.
How Is Asthma Treated
If you or a loved one has asthma, we can put together a comprehensive plan to treat it. This plan can address the particular allergens that affect you. Also, the frequency and severity of your symptoms will be factored into your plan.
Its common for an inhaler to be used in an asthma treatment plan. Its a portable device that can deliver a premeasured dose of asthma medicine into a patients lungs. Some inhalers have corticosteroids that can control swelling and irritation in the airway, while other inhalers have fast-acting drugs like bronchodilators which can help open up the airway quickly when necessary. A combination of medicines is possible. Inhalers are very effective for many patients, not just for seasonal use, but for daily use.
For some patients, a nebulizer can help, while for others, an oral medicine will help. Different medicines have different purposes, like reducing inflammation or helping to open up the airway, and its also possible to get an oral corticosteroid. Sometimes with more severe cases of asthma, a patient will benefit greatly from injections of a biologic medication that can reduce the patients sensitivity to allergens.
Some or many of the aforementioned treatments will be factored into your treatment plan with us at Allergy & Asthma Center. Together in your plan, the treatments can reduce or even relieve your symptoms so you can live the kind of life youve been missing.
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Foods And Dietary Supplements
Eating an overall healthful diet may be helpful for asthma and there are certain foods and supplements with potential to offer additional support. Whenever possible, opt for food sources of nutrients since supplements are largely unregulated by the U.S. Food and Drug Administration . They haven’t been tested for safety and it’s hard to know if the dosage and contents are consistent with the product label. Always discuss supplements with your physician since some are known to interact with medications.
Also, keep in mind that the safety of supplements in;pregnant women, nursing mothers, children, and those with medical conditions has not been established.
When buying supplements, look for those certified by ConsumerLabs, The U.S. Pharmacopeial Convention, or NSF International. It won’t guarantee that a product is safe or effective, but it ensures that there is some testing for quality.