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HomeExclusiveDoes Ibuprofen Make Asthma Worse

Does Ibuprofen Make Asthma Worse

What Pain Relievers Are Recommended

Paracetamol is the safest medication for occasional use to treat pain or colds and flu. 

Recent research has suggested that the longer term use of high doses of paracetamol can aggravate asthma. 

Aspirin or acetylsalicylic acid is freely available from supermarkets and pharmacies, and is widely used for the treatment of pain, fever and inflammation. 

It is particularly useful for rheumatic and arthritic conditions as well as reducing the risks of blood clotting. 

Apart from the possibility of severe reactions in some people with asthma, aspirin is a very useful drug that is both safe and effective. 

Examples of aspirin based products are: Aspec, Alka Seltzer, Aspro and Aspro Clear, Cardiprin, Cartia, Disprin, Codcomol, Solprin, Codral Forte, Pirophen. Examples of products containing salicylates are: Bonjela, Orased Jel, Applicaine.

The following medicines are Non-Steroidal Anti-Inflammatory Drugs that may trigger asthma in some people:

  • Ibruprofen
  • Naproxen
  • Keptoprofen
  • Diclofenac
  • Mefenamic Acid
  • Piroxicam
  • Diflunisal

People Who Cannot Take Ibuprofen

The NHS advises towards taking ibuprofen in case youve had an allergic response to it previously.

Symptoms of an allergic response may embody wheezing, a runny nostril or pores and skin reactions.

The nationwide well being physique additionally advises individuals with uncontrolled hypertension to avoid the painkiller.

To make certain ibuprofen is protected for you, do inform the pharmacist in case youve had any of the next well being points:

  • Stomach ulcer
  • A gap within the abdomen
  • Liver fibrosis
  • Crohns illness
  • Ulcerative colitis

Also focus on along with your GP in case youre capable of take ibuprofen in case youve had any of the well being points talked about above.

Other severe negative effects of ibuprofen may embody black poo or blood in your vomit, that are indicators of inner bleeding.

Also name your GP right away in case your ankles turn into swollen, theres blood in your urine otherwise youre not capable of urinate in any respect these are indicators of a kidney drawback.

Meanwhile, extreme chest or abdomen ache could possibly be indicative of a gap within the abdomen or intestine.

Common negative effects of the mediation can embody:

  • Headaches

How To Take Ibuprofen

Make sure you take ibuprofen as directed on the label or leaflet, or as instructed by a health professional.

How much you can take depends on your age, the type of ibuprofen you’re taking and how strong it is. For example:

  • adults can usually take 1 or 2 tablets  every 4 to 6 hours, but shouldn’t take more than 1,200mg  tablets in the space of 24 hours
  • children under 16 may need to take a lower dose, depending on their age; check the packet or leaflet, or ask a pharmacist or doctor for advice

The painkilling effect of ibuprofen begins soon after a dose is taken, but the anti-inflammatory effect can sometimes take up to 3 weeks to get the best results.

Ibuprofen shouldn’t be used to treat conditions that are mainly related to inflammation.

Don’t take more than the recommended dose if it isn’t relieving your symptoms.

Adults can take  at the same time if necessary, but this isn’t recommended for children.

Contact your GP or phone the NHS 24 111 service if your symptoms get worse or last more than 3 days despite taking ibuprofen.

What Are The Risks For People With Asthma

If you have asthma, painkillers called nonsteroidal anti-inflammatory drugs can be risky. They include aspirin, , , and ketoprofen, the active ingredients in medicines like , , and .

Other pain relievers are potentially less dangerous. — the active ingredient in — works differently. It poses a much lower risk of problems for people with asthma, although like any drug, it does have side effects of its own. You shouldn’t take any over-the-counter painkiller for more than 10 days without your health care provider’s approval.

Why are people with asthma at special risk from NSAIDs? Experts aren’t sure of the exact cause, but it seems that these medicines can trigger a dangerous immune response leading to constriction of the airways. People who are older and who have more severe asthma may be more sensitive to these drugs.

Symptoms include a , runny nose, shortness of breath, and wheezing. In some people, these medicines can also cause swelling of the face or . If you have any reaction, get help right away.

“One problem is that people may not realize the connection between asthma and a painkiller,” Korenblat tells WebMD. “It can take up to two hours for the medicine to cause the effect, so you may not see the link.”

Aspirin And Other Drugs That May Trigger Asthma

Painkiller warning: Ibuprofen may make asthma symptoms ...

Carol DerSarkissian, MD

Many people with have sensitivities to certain drugs that can precipitate an asthma attack . If you have , you need to be aware of which may be triggers. You do not need to avoid these medications unless you know they are asthma triggers for you. If these medications have never triggered your , it is still best to take the medications with caution because a reaction can occur at any time.

Below is a list of the most common medications known to trigger symptoms of asthma. However, if you are prescribed any medication that you think may be causing your asthma to worsen, discuss it with your doctor.

Aspirin Sensitivity, Asthma, and Nasal Polyps. Some people with asthma cannot take aspirin or NSAIDs because of whatâs known as Samterâs — a combination of asthma, aspirin sensitivity, and nasal polyps. Nasal polyps are small growths that form inside the nasal cavity.

This aspirin sensitivity occurs in about 30% to 40% of those who have asthma and nasal polyps. Many people with Samter’s triad have nasal symptoms, such as runny nose, postnasal drip, and congestion, along with asthma symptoms, such as wheezing, , and shortness of breath. Talk to your doctor about options other than aspirin and NSAIDs if you have this.

How To Cope With Side Effects

What to do about:

  • headaches â make sure you rest and drink plenty of fluids. Don’t drink too much alcohol. Talk to your doctor if they last longer than a week or are severe.
  • feeling dizzy â if ibuprofen makes you feel dizzy, stop what you’re doing and sit or lie down until you feel better. Avoid coffee, cigarettes and alcohol. If the dizziness doesn’t get better within a couple of days, speak to your pharmacist or doctor.
  • feeling sick â stick to simple meals. Do not eat rich or spicy food.
  • being sick â have small, frequent sips of water. Speak to a pharmacist if you have , such as peeing less than usual or having dark, strong-smelling pee. Don’t take any other medicines to treat without speaking to a pharmacist or doctor.
  • wind â try not to eat foods that cause wind . Eat smaller meals, eat and drink slowly, and exercise regularly. There are pharmacy medicines that can also help, such as charcoal tablets or simethicone.
  • indigestion â if you get repeated indigestion stop taking ibuprofen and see your doctor as soon as possible. If you need something to ease the discomfort, try taking an , but do not put off going to the doctor.

The Spreading Of Rumours Has Led To Confusion

Worries over the use of ibuprofen appear to have surfaced in France, after Jean-Louis Montastruc, a doctor at Toulouse University Hospital warned on Twitter that: “In this period of coronavirus, it is necessary to remember the risk of complications of the NSAIDs in case of fever or infection.”

A subsequent tweet by France’s health minister, Olivier Veran, saying that anti-inflammatory drugs “could be an aggravating factor of the infection” was shared more than 43,000 times. But he also said people should consult a doctor before stopping taking them.

Other tweets are also being shared including one saying that ibuprofen “may cause severe cases of the disease, even in young and middle-aged adults with no underlying conditions” which has been shared more than 94,000 times on Twitter.

A lack of clear consensus on the issue from the medical profession has led to mixed messages and rumours spreading online, and the University of Vienna laboratory claim noted earlier seems to have taken on a life of its own in both English and German.

Twitter and Facebook posts – which seem to be cut-and-pasted and adapted by users – all claim to have a “doctor in the family” who has information from the Vienna lab that “the vast majority of people who died of Covid-19 had ibuprofen in their system”. Some of the posts go on to claim that coronavirus “thrives on ibuprofen”. There is no evidence that this is the case.

Reporting by Rachel Schraer, Jack Goodman and Alistair Coleman

What About Aspirin And Other Pain Relievers

Aspirin and drugs called nonsteroidal anti-inflammatory drugs may be harmful in people with asthma. Ibuprofen , naproxen and ketoprofen are examples of NSAIDs. If you are allergic to aspirin, ask your doctor or pharmacist to make sure any new medicine you might take is not related to aspirin.

Most times, acetaminophen can be taken by people with asthma. This medicine is used for fever and pain. Very rarely, even acetaminophen may make asthma worse. If this happens to you, tell your doctor.

All These Claims Are False

The Infectious Diseases Society of Ireland said a WhatsApp message circulating about coronavirus patients in Cork is “a fake message”, asking anyone who receives it to “ignore and delete”.

Toulouse University Hospital warned that inaccurate information was circulating on social networks, saying it would not have discussed the care of patients due to medical confidentiality.

Angiotensin Converting Enzyme Inhibitors

ACE inhibitors are commonly used medicines for the treatment of high blood pressure and heart failure. Common generic-brand forms include lisinopril, ramipril, and many other forms ending in the letters pril. and However, some people have respiratory side effects from this class of medicine, with approximately 10% having a nagging, dry cough. This cough can be mistaken for worsening asthma or other common causes of a cough. Generally, the cough will go away within a few weeks of stopping the ACE inhibitor. However, if a cough is severe, or the ACE inhibitor cannot be stopped, inhaled cromolyn or nedocromil may be useful to treat an ACE inhibitor-induced cough.

Painkiller Warning: Ibuprofen May Make Asthma Symptoms Worse

Available in pill type, capsules, syrup, and gels, in addition to mousses and sprays, ibuprofen is a well-liked painkiller many flip to in instances of want. You may even discover the ingredient mixed with some chilly and flu treatments. Yet not everybody must be taking it. Oral administration of the drug can take as much as half-hour to cut back hormones within the physique that trigger ache and swelling, stated the NHS. If you discover that your asthma symptoms worsen after taking ibuprofen, that you must discuss to your GP.

Asthma: Will Ibuprofen Affect Me

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I have both asthma and arthritis. The arthritis is quite painful, but when I try to buy ibuprofen from a pharmacist, they refuse because I have asthma. I have taken ibuprofen many times with no problems. Should I avoid it?

Dr Fred Kavalier answers your health question:

About 20 per cent of adults with asthma have what is called aspirin induced asthma. They develop potentially severe asthma symptoms if they take aspirin or non-steroidal anti-inflammatories such as ibuprofen. Asthmatics who are sensitive to aspirin and NSAIDs often have nasal polyps, an allergic skin rash called urticaria, and chronic nasal allergies. If you have ever had an allergic or asthmatic reaction to these drugs, you should never take them again. But if you are over 40 and have taken ibuprofen with no problems, the risk in taking it again is very small. As a rule, asthmatics should use paracetamol. If you really need ibuprofen, be aware of any effect it has on your asthma. If you ever feel it makes it worse, do not take it. All children, asthmatic or not, should avoid aspirin.

Whats The Risk In Taking Ibuprofen If You Have Asthma

Painkiller warning: Ibuprofen may make asthma symptoms ...

If you have asthma, but arent aspirin-sensitive, you should be able to take ibuprofen as directed.

If you do have aspirin-sensitive asthma, ibuprofen can trigger symptoms of asthma or allergy. Symptoms of severe allergic reaction usually develop within a few hours after taking the drug. Some of them are:

  • nasal congestion, runny nose

If youre ibuprofen-sensitive, its important to scrutinize medicine labels carefully. Avoid products that contain ibuprofen, aspirin, or any other .

people with asthma can safely take acetaminophen to treat fever or pain.

Certain asthma medications block leukotrienes. These include zafirlukast , montelukast , and zileuton . Ask your doctor if these medicines affect your ability to take ibuprofen. Your doctor can also guide you on the safest pain relievers, potential side effects, and what to do if you have an allergic reaction.

For frequent or chronic pain, your doctor may be able to provide alternate solutions based on the cause.

If youve had a bad reaction in the past and accidentally take ibuprofen, contact your doctor right away. Seek emergency medical care or call 911 if you have symptoms of severe allergic reaction such as:

  • facial swelling

How Often Should You Use Albuterol

Only use your rescue inhaler when youre experiencing asthma symptoms. It doesnt take the place of your maintenance medication.

Your doctor will provide you with specific information regarding when and how you should use albuterol. Always be sure to carefully follow their instructions.

Generally, the recommendation will be two puffs every four to six hours when youre experiencing symptoms. Some people may only need one puff instead of two.

If youre using your rescue inhaler three or more times per week, you likely need a better maintenance regimen.

Medications That Can Worsen Asthma

When we think of triggers for asthma, the use of medicines for other medical problems doesnt usually come to mind. Usually, medicines help a persons medical conditionsdoesnt worsen them. However, there are some medicines that a person can take that can worsen asthma symptoms, or cause other respiratory symptoms such as coughing. Therefore, it is important that you inform each and every doctor that treats you about your asthma and other medical problems.

Search Strategy And Study Selection

The search strategy was conducted in PubMed, Science Citation Index, Embase, Cochrane library, and . The following search terms were included AND ibuprofen AND . All databases were searched from their inception until September 2017. The search was updated in July 2019 and was supplemented with a PubMed similarity search as well as a forwards and backwards citation search for the articles included in the meta-analysis. The references lists from relevant systematic reviews and meta-analyses were hand searched.

Eligible studies were RCTs conducted in humans that included paracetamol and ibuprofen within their study arms. To be considered for inclusion, the RCTs had to include children and reported the number of cases of wheezing, asthma and/or asthma exacerbations. The outcome of interest could be reported either as the primary or secondary outcome or as an adverse event in the RCT. Studies were excluded if the study arms included co-interventions . No language restriction was applied. Two authors independently screened the articles. Disagreement was resolved through consensus.

Other Options For Pain Relief

Of course, painkillers aren’t the only answer for many of life’s aches and pains. Many effective and safe alternatives don’t have any side effects at all.

  • Ice packs, for acute injuries like a sprained ankle, can keep down swelling and ease pain.
  • Heat — with a hot towel or heating pad — can be helpful for treating chronic overuse injuries.
  • Physical activity can help reduce some kinds of discomfort, such as arthritis pain.
  • Relaxation — with techniques like or meditation — may reduce pain. may help as well. These approaches are best for pain that’s made worse by stress, like tension .
  • Nontraditional techniques with low risks — like — benefit some people.

So remember: Pain relief doesn’t only come from a pill bottle.

How Does Ibuprofen Affect Asthma

According to ibuprofens package insert, you shouldnt take it if you have experienced asthma, urticaria , or an allergic reaction after taking an NSAID. If you have asthma and are aspirin-sensitive, using these products may cause severe , which can be life-threatening.

Ibuprofen and other NSAIDs work by inhibiting a protein called cyclooxygenase. Its not clear why some people with asthma are overly sensitive to these inhibitors.

It may be related to overproduction of chemicals called leukotrienes. In people with asthma, leukotrienes are released into the airways by allergy cells in the bronchial tubes. This causes bronchial muscles to spasm and bronchial tubes to swell.

The reason some people with asthma produce too many leukotrienes isnt well understood.

Ibuprofen is sold under a variety of brand names, including:

  • Advil
  • Motrin
  • Nuprin

Many combination drugs contain ibuprofen. These include medicines for cold and flu, sinus problems, and stomach upset. Other OTC NSAIDs include:

  • aspirin
  • naproxen

Others are available by prescription.

Approximately 5 percent of people with asthma are sensitive to NSAIDs. Most are adults.

Some people have asthma, aspirin intolerance, and nasal polyps. This is known as aspirin exacerbated respiratory disease . If you have ASA triad, NSAIDs can cause a severe, even life-threatening reaction.

What About Other Medicines Im Taking

Any medicine can cause wheezing or shortness of breath if you are allergic to it. If you notice that your asthma gets worse every time you take a certain medicine, tell your doctor as soon as possible. If you use a peak flow meter to check your asthma, remember to use it if you think your asthma is worse. If you see changes in your peak flow readings after you take a certain medicine, tell your doctor. Your doctor can decide if your medicine should be changed.

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Who Can Take Ibuprofen

Some people should avoid using ibuprofen and others should use it with caution. If you have any queries about using ibuprofen or any other medicines, speak to your GP or pharmacist, or phone the NHS 24 111 service.

You shouldn’t take ibuprofen if you:

  • have a history of a strong, unpleasant reaction to aspirin or other 
  • have a current or recent stomach ulcer, or you have had one in the past

Will Aspirin And Other Pain Relievers Make My Asthma Worse

Acetaminophen vs. Ibuprofen: Giving Tylenol To Children ...

Aspirin and other drugs called nonsteroidal anti-inflammatory drugs may be harmful for people who have asthma. Ibuprofen and naproxen are a few examples of NSAIDs. If you are allergic to aspirin, ask your doctor or pharmacist to make sure any new medicine you might take is not related to aspirin.

People who have asthma can usually take acetaminophen safely. This medicine is typically used to relieve fever and pain. Very rarely, even acetaminophen may make asthma worse, which has prompted further studies to explore the link between acetaminophen and asthma. If acetaminophen makes your asthma worse, tell your doctor. He or she can help you find another type of pain reliever.

What If I Forget To Take It

If you are prescribed ibuprofen as a regular medicine and forget to take a dose, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose and take your next dose as normal.

Never take a double dose to make up for a forgotten one.

If you often forget doses, it may help to set an alarm to remind you. You could also ask your pharmacist for advice on other ways to help you remember to take your medicine.

Side Effects Of Gel Mousse And Spray

You’re less likely to have side effects when you apply ibuprofen to your skin than with tablets, capsules and syrup because less gets into your body. However, you may still get the same side effects, especially if you use a lot on a large area of skin.

Applying ibuprofen to your skin can also cause your skin to become more sensitive than normal to sunlight.

These are not all the side effects of ibuprofen gel, mousse and spray. For a full list see the leaflet inside your medicines packet.

The Pros And Cons Of Pain

For those times when you do need a dose of pain relief, you need to make a smart choice. Here’s a rundown of the benefits and risks of some popular pain . It should help simplify your choices the next time you’re in the drugstore.

Keep in mind that you shouldn’t use any over-the-counter painkiller on a regular basis. If you’re in that much pain, you need to talk with your health care provider.


ASPIRINBayer, Bufferin,

Asthmatics With Nasal Polyps Should Avoid Nsaids; Others Use With Caution

NSAID-induced bronchospasm should be suspected in any patient whose asthma control worsens on initiation of a NSAID. Patients with a history of asthma should be warned of this reaction and to seek medical help if symptoms worsen on initiation of a NSAID.

NSAIDs should be used with caution in the presence of asthma and avoided in asthmatics with nasal polyps. As it is difficult to identify ‘at risk’asthmatics, it would seem prudent to prescribe paracetamol instead of aspirin unless there are any specific contra-indications.

Patients should be reminded to read labels of over-the-counter medicines as some, such as cough/cold preparations, may contain aspirin. Ibuprofen, diclofenac and other NSAIDs are also available over-the-counter.

  • Ayres JG, Fleming DM, Whittington RM. Asthma death due to ibuprofen. Lancet 1987;1:1082.
  • Bosso JV, Creighton D, Stevenson DD. Flurbiprofen cross-sensitivity in an aspirin-sensitive asthmatic patient. Chest 1992;101:856-858.
  • Chen AH, Bennett CR. Ketorolac-induced bronchospasm in an aspirin-intolerant patient. Anesth Prog 1994;41:102-107.
  • Zikowski D, Hord AH, Haddox JD, Glascock J. Ketorolac-induced bronchospasm. Anesth Analg 1993;76:417-419.
  • Slepian IK, Mathews KP, McLean JA. Aspirin-sensitive asthma.Chest 1985;87:386-391.
  • Power I. Aspirin-induced asthma Brit J Anaes1993;71:619-620.
  • Sitenga GL, Ing EB, Van Dellen RG, et al. Asthma caused by topical application of ketorolac. Ophthalmology 1996;103:890-892.

    Aspirin Exacerbated Respiratory Disease

    Aspirin-induced asthma, Samter’s triad, Samter’s syndrome, nonsteroidal anti-inflammatory drugs-exacerbated respiratory disease
    Aspirin in coated tablets

    Aspirin exacerbated respiratory disease , also termed aspirin-induced asthma, is a medical condition initially defined as consisting of three key features: , respiratory symptoms exacerbated by and other nonsteroidal anti-inflammatory drugs , and nasal polyps. The symptoms of respiratory reactions in this syndrome are hypersensitivity reactions to NSAIDs rather than the typically described true allergic reactions that trigger other common -induced asthma, rhinitis, or hives. The NSAID-induced reactions do not appear to involve the common mediators of true allergic reactions, immunoglobulin E or T cells. Rather, AERD is a type of NSAID-induced hypersensitivity syndrome. EAACI/WHO classifies the syndrome as one of five types of NSAID hypersensitivity or NSAID hypersensitivity reactions.

    What Are My Other Pain Relief Options If I Have Asthma

    If you have asthma, discuss your pain relief options with your doctor. Your doctor may suggest options for pain relief that are suitable for you.

    This medicine may not be right for you. Read the label before purchase. Follow the directions for use. Incorrect use could be harmful. If symptoms persist, talk to your health professional.


    When To See A Doctor

    Plan to talk to your doctor if youre using albuterol three or more days a week, or if you find that you go through an entire canister in one month.

    Having to use your rescue inhaler more frequently can be a sign that your maintenance medication isnt managing your asthma well. Your doctor can work with you to adjust your treatment plan so you have to use your rescue inhaler less often.

    Taking Ibuprofen With Other Painkillers

    Ibuprofen and Asthma: Interactions and Warnings

    It’s safe to take ibuprofen with or .

    But do not take ibuprofen with similar painkillers like or without talking to a pharmacist or doctor.

    Ibuprofen, aspirin and naproxen belong to the same group of medicines called non-steroidal anti-inflammatory drugs . If you take them together, ibuprofen plus aspirin or naproxen may increase the chance of you getting side effects like stomach ache.

    NSAIDs are also used in medicines you can buy from pharmacies â for example, cough and cold remedies. Before taking any other medicines, check the label to see if they contain aspirin, ibuprofen or other NSAIDs.


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